Linear mixed model (LMM) methodology is a powerful technology to analyze models containing both the fixed and random effects. The model was first proposed to estimate genetic parameters for unbalanced ...

Response-adaptive designs are important alternatives to equal allocation in clinical trials because equal treatment allocation has been found to have ethical issues. In this article we discuss the ...

This is a preview. Log in through your library . Abstract The generalized linear mixed model (GLMM), which extends the generalized linear model (GLM) to incorporate random effects characterizing ...

In this module, we will introduce generalized linear models (GLMs) through the study of binomial data. In particular, we will motivate the need for GLMs; introduce the binomial regression model, ...